The carcinogenic potential of a substance is influenced by several factors: the dose, route of exposure, duration of exposure, and individual susceptibility. A dose-response relationship is often observed, where the risk of cancer increases with the level of exposure. Different routes of exposure, such as inhalation, ingestion, or dermal contact, can also result in varying levels of risk. Additionally, genetic factors and lifestyle choices such as smoking and diet can affect an individual's susceptibility to carcinogens.