Several factors can influence cumulative exposure:
1. Duration of Exposure: Longer exposure periods generally result in higher cumulative exposure. 2. Frequency of Exposure: Frequent exposure increases the total amount of toxicant accumulated in the body. 3. Concentration of the Toxicant: Higher concentrations lead to greater cumulative exposure. 4. Route of Exposure: The way a toxicant enters the body (inhalation, ingestion, dermal contact) can affect its absorption and accumulation. 5. Individual Susceptibility: Genetic factors, age, gender, and overall health can influence how an individual metabolizes and eliminates toxicants.