Several factors can influence the efficiency of detoxification, including:
- Genetic Variability: Genetic differences can affect enzyme activity levels, influencing how individuals metabolize and detoxify toxins. - Nutritional Status: Nutrients such as vitamins, minerals, and amino acids are essential cofactors for detoxification enzymes. Deficiencies can impair detoxification pathways. - Age and Gender: Metabolic rates and enzyme activities can vary with age and between genders, affecting detoxification. - Exposure Levels: The extent and duration of exposure to toxins can overwhelm the detoxification systems, leading to accumulation and toxicity.