Several factors influence dose calculation, including:
Body Weight: Larger individuals may require higher doses for the same effect. Age: Children and the elderly may have different sensitivities to substances. Route of Exposure: Inhalation, ingestion, and dermal contact can result in different bioavailability. Duration of Exposure: Acute (short-term) versus chronic (long-term) exposure can lead to different outcomes. Metabolic Rate: Metabolism can influence how quickly a substance is absorbed, distributed, metabolized, and excreted.
