Several factors can influence the uptake of a toxicant. These include:
Chemical Properties: The lipophilicity, molecular size, and ionization state of a chemical can affect its ability to penetrate biological membranes. Biological Factors: The age, health status, and genetic makeup of an organism can alter uptake rates. For example, individuals with certain genetic polymorphisms may absorb toxicants differently. Environmental Conditions: The presence of other chemicals, pH levels, and temperature can modify the uptake of substances.