Several factors can influence the determination of a safe dosage, including:
Age and Body Weight: Dosage may vary based on age and weight because children and the elderly often metabolize substances differently. Genetic Factors: Genetic variations can affect how individuals respond to certain chemicals and drugs. Gender: Hormonal differences can result in variable effects and responses to chemicals in males and females. Health Status: Individuals with pre-existing health conditions may have a different tolerance to certain substances. Exposure Route: The way a substance enters the body (oral, inhalation, dermal) can impact its toxicity.