What Factors Influence Toxin Distribution in the Circulatory System?
Several factors influence how toxins are distributed throughout the circulatory system. Lipid solubility of the toxin affects its ability to cross cell membranes and accumulate in fatty tissues. The presence of specific binding sites in the blood, such as plasma proteins, can affect the free concentration of the toxin, impacting its distribution and toxicity. Furthermore, blood flow rates to different tissues can determine the extent and speed of toxin distribution.
