In the field of toxicology, Annex III refers to a specific component of international chemical management frameworks, most notably under the Rotterdam Convention. This annex plays a crucial role in identifying substances that require special consideration due to their toxicity and potential risks to human health and the environment. Annex III lists chemicals that are subject to the Prior Informed Consent (PIC) procedure, ensuring that countries have the necessary information to make informed decisions about the import and management of hazardous chemicals.