Delayed type hypersensitivity (DTH) is a type of immune response that occurs later than the immediate reactions, usually manifesting 24-72 hours after exposure to an antigen. It is primarily mediated by T-cells rather than antibodies, distinguishing it from other types of hypersensitivity reactions. DTH is a vital component of the immune system's ability to fight off certain pathogens, but it can also be implicated in adverse reactions to certain chemicals and drugs in the field of Toxicology.