What is GFR and Why is it Important in Toxicology?
GFR measures how well the kidneys filter blood, removing waste and excess substances. It is expressed in milliliters per minute (mL/min) and provides a quantitative assessment of kidney function. In toxicology, GFR is important because it indicates how efficiently the kidneys can clear toxins from the body. A reduced GFR can lead to the accumulation of toxic substances, exacerbating their effects.