What is the Clinical Significance of Mallory Bodies?
The presence of Mallory bodies in liver biopsy samples is clinically significant as it indicates liver cell injury and suggests exposure to hepatotoxic agents. In patients with a history of alcohol use, their presence supports the diagnosis of alcoholic liver disease. In cases where alcohol is not a factor, Mallory bodies may point to other underlying liver conditions or toxic exposures. Their detection helps clinicians determine the etiology of liver disease and guide appropriate management strategies.