What is the Difference Between Graded and Quantal Dose-Response Curves?
In toxicology, dose-response curves can be classified as either graded or quantal. Graded dose-response curves represent continuous responses, such as enzyme activity or blood pressure changes, and are measured in a single organism. On the other hand, quantal dose-response curves are used for all-or-nothing responses, such as death or the presence of a specific symptom, across a population. These curves are essential for determining population-wide responses to a toxicant.