The future of ToxCast is promising, with ongoing efforts to refine and expand its capabilities. Advances in computational toxicology and machine learning are expected to enhance the accuracy and predictive power of the program. Additionally, the development of new assays and the integration of omics technologies (such as genomics, proteomics, and metabolomics) may provide more comprehensive insights into chemical toxicity. As ToxCast evolves, it will continue to play a crucial role in advancing toxicology and improving chemical safety assessments.