What is the Impact of Genetic Variability on Opioid Receptor Function?
Genetic variability can significantly impact opioid receptor function and individual responses to opioids. Polymorphisms in the genes encoding opioid receptors can lead to variations in receptor density, binding affinity, and signal transduction. This variability can influence susceptibility to opioid addiction, effectiveness of pain relief, and risk of adverse effects, highlighting the importance of personalized approaches in opioid therapy.
