What is the impact of lifestyle choices on susceptibility?
Lifestyle choices such as diet, smoking, and alcohol consumption can modulate susceptibility to diseases following toxicant exposure. For example, a diet high in antioxidants may enhance the body's ability to neutralize free radicals generated by toxicants, thereby reducing disease risk. Conversely, smoking and excessive alcohol intake can exacerbate toxic effects by impairing liver function and overwhelming detoxification pathways, increasing susceptibility to diseases like liver cirrhosis and respiratory disorders.