Assessing and managing susceptibility involves a combination of biomonitoring, genetic testing, and epidemiological studies. Biomarkers of exposure and effect can provide insights into the levels of toxicants in the body and their biological impact. Genetic testing can identify individuals with increased susceptibility due to specific genetic polymorphisms. Public health strategies, including regulatory measures and educational campaigns, are essential to minimize exposure and mitigate the effects of toxicants on susceptible populations.