What Is the Impact of Metabolism on Polyphenol Toxicity?
The metabolism of polyphenols plays a crucial role in determining their bioavailability and potential toxicity. Polyphenols are metabolized by the liver and the gut microbiota, leading to the formation of various metabolites that can differ significantly in their biological activity. The metabolic processes can either detoxify or activate polyphenols, influencing their toxicological profile.
