Humans can be exposed to brevetoxins primarily through the consumption of contaminated shellfish, leading to a condition known as Neurotoxic Shellfish Poisoning (NSP). Symptoms of NSP include nausea, vomiting, diarrhea, and neurological effects such as tingling sensations and ataxia. Inhalation of aerosolized brevetoxins, especially during red tide blooms, can cause respiratory irritation and exacerbate asthma symptoms in susceptible individuals.