What is the Role of cAMP in Cellular Defense Mechanisms?
cAMP is integral to cellular defense mechanisms against toxic agents. It can promote the expression of detoxifying enzymes and antioxidant proteins, enhancing the cell's ability to cope with oxidative stress and other toxic insults. The cAMP response element-binding protein (CREB) is a key transcription factor activated by cAMP that regulates the expression of genes involved in cell survival and repair. Thus, maintaining optimal cAMP levels is crucial for effective cellular defense.