human leukocyte antigen

What is the Role of HLA in Chemical Sensitivity?


HLA alleles can also affect susceptibility to chemical sensitivities. Individuals with specific HLA types may be more prone to developing hypersensitivity reactions to chemicals such as metals, fragrances, or pesticides. This is due to the HLA-mediated presentation of chemical-modified peptides that activate the immune response, resulting in allergic reactions or contact dermatitis.

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