What is the significance of the intrinsic pathway in toxicology?
The intrinsic pathway is significant in toxicology for several reasons. It helps to elucidate the mechanisms by which toxicants induce cell death, providing insight into potential therapeutic targets for preventing or mitigating damage. Moreover, dysregulation of this pathway is implicated in various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases, where abnormal apoptosis can either contribute to cell loss or allow harmful cells to survive. Therefore, a thorough understanding of the intrinsic pathway aids in the development of strategies to counteract the adverse effects of toxicants.
