Uridine 5'-diphospho-glucuronosyltransferases (UGTs) are a family of enzymes primarily involved in the process of glucuronidation, a major phase II metabolic pathway. This pathway plays a critical role in the detoxification and elimination of both endogenous substances and xenobiotics, including drugs and environmental toxins. UGT enzymes add glucuronic acid to lipophilic molecules, making them more water-soluble and easier to excrete through urine or bile.
