Various methods are employed to assess genotoxicity, including in vitro and in vivo assays. Common in vitro tests include the Ames test, which detects mutagenic potential in bacteria, and the Comet assay, which measures DNA strand breaks in individual cells. In vivo tests, such as the Micronucleus test, are conducted on living organisms to observe chromosomal damage or loss. These tests are vital for a comprehensive assessment of genotoxic potential.