What Questions are Addressed by One vs One Analysis?
What is the threshold dose? The analysis helps determine the minimum amount of toxicant needed to elicit a harmful effect on the organism. What are the toxic effects? Identification of specific physiological or biochemical changes in the organism resulting from exposure to the toxicant. What is the mechanism of action? Understanding the biochemical interactions and pathways through which the toxicant exerts its effects. Are there vulnerable populations? Identifying if certain groups within the species are more susceptible to the toxicant.
