Cytokines are critical in mediating the body's response to harmful substances, such as toxins. When a toxin enters the body, it can trigger an immune response, leading to the release of cytokines. This release can result in cytokine storm, an excessive and uncontrolled release of cytokines, which can cause significant tissue damage and lead to various diseases. Understanding the role of cytokines in these processes can help in developing strategies to mitigate their harmful effects.