What Role do Drug Interactions Play in Lamotrigine Toxicity?
Drug interactions significantly influence lamotrigine toxicity. Enzyme inducers such as phenytoin and carbamazepine can lower lamotrigine levels, potentially reducing efficacy. Conversely, enzyme inhibitors like valproate can increase lamotrigine levels, heightening the risk of toxicity. Adjusting doses accordingly and monitoring drug levels can help manage these interactions effectively.
