What Role Do Enzymes Play in Molecular Toxicology?
Enzymes play a critical role in the metabolism of toxicants. They are responsible for the biotransformation of toxic substances, making them more water-soluble and easier to excrete from the body. The most important enzymes in this process are the cytochrome P450 family, which catalyzes the oxidation of organic substances. However, enzymatic transformation can sometimes convert non-toxic substances into toxic metabolites, leading to adverse effects.
