What Role Do Isoprostanes Play in Disease Mechanisms?
Isoprostanes are involved in several disease mechanisms due to their ability to reflect oxidative stress. In atherosclerosis, elevated levels of isoprostanes indicate increased lipid peroxidation, contributing to the formation of atherosclerotic plaques. In neurodegenerative diseases like Alzheimer's, isoprostanes can exacerbate neuronal damage by enhancing inflammatory pathways. Thus, they are not only markers but also mediators in various pathophysiological processes.
