What Role Do Reactive Oxygen Species (ROS) Play in Toxicity?
Reactive oxygen species (ROS) are highly reactive molecules that can damage cellular components such as lipids, proteins, and DNA. Toxicants that induce oxidative stress can lead to the overproduction of ROS, overwhelming the cell's antioxidant defenses. This oxidative damage is implicated in various toxicological outcomes, including carcinogenesis, neurodegeneration, and cardiovascular diseases.
