What Role Does Angiotensin II Play in Hypertension?
Hypertension is one of the most significant toxicological concerns associated with angiotensin II. As a potent vasoconstrictor, angiotensin II increases peripheral resistance, leading to elevated blood pressure. This persistent high blood pressure can cause damage to blood vessels and organs, increasing the risk of stroke, heart attack, and kidney failure. Antihypertensive drugs, such as angiotensin receptor blockers (ARBs) and ACE inhibitors, target the renin-angiotensin system to mitigate these effects.
