Aspirin, a widely used analgesic and antipyretic, is implicated in the development of Reye's Syndrome in children and teenagers. When administered during viral infections, aspirin can lead to mitochondrial damage in the liver, resulting in hepatic encephalopathy and other metabolic disturbances characteristic of Reye's Syndrome. This connection has led to widespread recommendations against the use of aspirin in individuals under 18 during viral illnesses.
