What Role Does Epigenetics Play in Differentiation and Toxicology?
Epigenetics involves changes in gene expression that do not involve alterations to the underlying DNA sequence. These changes can significantly impact cellular differentiation. Toxicants can induce epigenetic modifications, such as DNA methylation and histone modification, leading to altered cell differentiation. Understanding these epigenetic changes is crucial for assessing long-term and transgenerational effects of chemical exposures.
