What Role Does Metabolism Play in Systemic Absorption?
After systemic absorption, metabolism plays a key role in determining the ultimate fate of a substance. The liver is the primary site for metabolism, where substances can be transformed into more water-soluble compounds for easier excretion. Metabolic processes can either detoxify harmful substances or, in some cases, activate them into more toxic forms. Understanding these pathways is vital for evaluating the overall toxicity of a compound.
