What components make up the tumor microenvironment?
The TME is composed of a multitude of components, including cancer cells, stromal cells such as fibroblasts, immune cells like macrophages and lymphocytes, blood vessels, and the extracellular matrix. Each of these elements plays a role in modulating tumor behavior and its interaction with external substances, including toxins and drugs. The interplay between these components can affect cellular signaling pathways, growth dynamics, and immune evasion strategies.
