What Role Does the Hypothalamus Play in Neurotoxicity?
The hypothalamus is particularly vulnerable to neurotoxic agents due to its role in neuroendocrine regulation. Neurotoxins can disrupt the synthesis and release of hypothalamic hormones, affecting downstream endocrine organs. For example, disruption in the hypothalamic-pituitary-adrenal (HPA) axis due to toxic exposure can lead to altered stress responses and immune function, highlighting the interconnectedness of hypothalamic health and overall body function.