What Role Does the MAPK Pathway Play in Toxicology?
In toxicology, the MAPK pathway is crucial for mediating cellular responses to various toxicants. It can influence cell survival, apoptosis, and adaptation to stress. For instance, exposure to heavy metals, such as arsenic or mercury, can activate the MAPK pathway, leading to inflammation, oxidative stress, and cell death. Understanding how toxicants modulate the MAPK pathway enables toxicologists to predict potential risks and design strategies to mitigate harmful effects.
