Several substances are associated with changes in OAE responses, indicating potential ototoxic effects. These include:
Aminoglycoside antibiotics: These antibiotics can cause damage to the cochlear hair cells, leading to reduced or absent OAEs. Cisplatin: This chemotherapeutic agent is well-documented for its ototoxic effects, often resulting in permanent hearing loss. Loop diuretics: Medications like furosemide can cause temporary changes in OAEs, although these changes are often reversible. Solvents: Occupational exposure to solvents like toluene and styrene has been linked to altered OAE patterns.
