Superinfection is primarily caused by the disruption of the normal microbial flora. This disruption can occur due to the administration of antimicrobial agents that target specific pathogens but inadvertently affect other non-targeted organisms. This creates an imbalance, allowing opportunistic pathogens to thrive. In the context of toxicology, exposure to certain toxic chemicals can also impair the immune system, further facilitating the occurrence of superinfections.
