Antidotes are specific treatments for certain toxins and play a key role in toxicology management. Their use is indicated when the toxin is known, and an effective antidote exists. Some common antidotes include N-acetylcysteine for acetaminophen toxicity, naloxone for opioid overdose, and atropine for organophosphate poisoning. The decision to use an antidote depends on the poisoning severity and the availability of the antidote.