Which Chemicals are Known to Cause Genomic Instability?
Several chemicals have been identified as causing genomic instability. These include ionizing radiation, which causes direct DNA breaks, and polycyclic aromatic hydrocarbons (PAHs), which form DNA adducts. Heavy metals like arsenic, cadmium, and lead can interfere with DNA repair processes. Furthermore, chemotherapeutic agents, while targeting rapidly dividing cancer cells, can also induce instability, affecting normal cells.
