Which CYP Enzymes are Most Relevant in Toxicology?
While there are many CYP enzymes, a few are particularly relevant in the context of toxicology. CYP3A4 is the most abundant in the liver and metabolizes approximately 50% of all drugs. Others, such as CYP2D6, CYP2C9, and CYP1A2, also play significant roles in drug and toxin metabolism.
