Why Are Heterodimers Important in Drug Metabolism?
Heterodimers are particularly important in the context of drug metabolism as they can affect the activity of enzymes responsible for the biotransformation of drugs and other xenobiotics. For example, cytochrome P450 enzymes, which are often involved in the formation of heterodimers, play a critical role in the metabolism of a wide range of chemicals. Alterations in these heterodimeric interactions can lead to variations in drug efficacy and toxicity.
