individual variabilities

Why Do Individuals Respond Differently to Toxic Substances?

Several factors contribute to individual differences in response to toxicants:
Genetic Factors: Genetic makeup can influence how a person metabolizes and responds to toxins. Specific genes may encode enzymes that alter the efficacy of detoxification processes.
Age and Sex: Age can impact the body's ability to handle toxins, with infants and the elderly often being more vulnerable. Additionally, hormonal differences between sexes can affect susceptibility.
Lifestyle and Diet: Diet, physical activity, and habits such as smoking or alcohol consumption can modify the body's response to toxic substances.
Health Status: Pre-existing health conditions can exacerbate or mitigate the effects of toxic substances. For example, individuals with liver or kidney disease may experience increased toxicity.

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