Understanding ADME processes is crucial for several reasons. Firstly, it helps in predicting bioavailability, which is the fraction of an administered dose that reaches the systemic circulation. Secondly, it aids in identifying potential toxicokineticsâhow the body handles toxic substances over time. Thirdly, it assists in the development of therapeutic interventions to mitigate toxicity, such as antidotes or supportive care measures.
