Cholinesterase activity is a vital biomarker in toxicology because its inhibition is associated with exposure to certain toxic substances, particularly organophosphates and carbamates. These chemicals are commonly found in pesticides and nerve agents. Inhibition of cholinesterase leads to the accumulation of acetylcholine at nerve synapses, resulting in continuous nerve stimulation, which can cause symptoms ranging from mild (e.g., headaches, dizziness) to severe (e.g., respiratory failure, convulsions).
