inhibitory neurotransmitters

Why is GABA Important in Toxicology?

GABA is the primary inhibitory neurotransmitter in the central nervous system. It plays a pivotal role in reducing neuronal excitability and preventing overstimulation. GABAergic system disruption is implicated in various toxicological syndromes. For example, exposure to strychnine, a known GABA antagonist, can lead to severe muscle contractions and convulsions due to the removal of inhibitory controls.

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