Why is Homologous Recombination Important in Toxicology?
In the field of toxicology, HR is crucial because it helps cells cope with damage induced by environmental toxins, chemicals, and radiation. For instance, exposure to ionizing radiation or certain chemotherapeutic agents can cause DSBs. Understanding HR allows researchers to evaluate the genotoxic potential of such agents and develop strategies to mitigate their harmful effects. Moreover, HR's role in preventing oncogenic mutations is central to understanding chemical carcinogenesis.
