non specific binding

Why is Non-Specific Binding Important in Toxicology?

In toxicological studies, non-specific binding can influence the distribution, metabolism, and excretion of toxins. It can lead to an overestimation or underestimation of the effective concentration of a compound, impacting the assessment of its toxicity. This phenomenon is especially relevant in the development of therapeutic drugs, as it can affect both efficacy and safety profiles.

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