Non-specific binding occurs when a molecule, such as a drug or toxin, binds to sites other than its intended biological target. These sites can include proteins, lipids, or other macromolecules within the body. Such interactions are typically characterized by weak forces like hydrogen bonding, van der Waals forces, or electrostatic interactions. Unlike specific binding, non-specific binding does not lead to a biological effect or response but can interfere with the intended action of a compound.