In toxicology, accurate diagnosis of toxin exposure is critical. Misdiagnosis can lead to unnecessary treatments or missed interventions. High NPV is essential for screening tests used in populations with low prevalence of a condition, as it ensures that individuals who test negative are indeed not at risk.
For instance, in occupational toxicology, where workers might be exposed to hazardous substances, a test with a high NPV can confidently rule out exposure, ensuring that workers are not subjected to unnecessary medical interventions.